Antimicrobial quaternary ammonium organosilane cross-linked nanofibrous collagen scaffolds for tissue engineering

• Main Authors: Dhand, Chetna, Balakrishnan, Yamini, Ong, Seow Theng, Dwivedi, Neeraj, Venugopal, Jayarama Reddy, Harini, Sriram, Leung, Chak Ming, Low, Kenny Zhi Wei, Loh, Xian Jun, Beuerman, Roger W., Ramakrishna, Seeram, Verma, Navin Kumar, Lakshminarayanan, Rajamani
• Format: Article
• Language: English
• Published: Dovepress 2018
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/29827/1/Antimicrobial%20quaternary%20ammonium%20organosilane%20cross-linked%20nanofibrous%20collagen.pdf; http://umpir.ump.edu.my/id/eprint/29827/; https://doi.org/10.2147/IJN.S159770; https://doi.org/10.2147/IJN.S159770

Introduction: In search for cross-linkers with multifunctional characteristics, the present work investigated the utility of quaternary ammonium organosilane (QOS) as a potential cross-linker for electrospun collagen nanofibers. We hypothesized that the quaternary ammonium ions improve the electrosp...