Antibacterial and antibiofilm properties of ZnO nanoparticles synthesis using gum arabic as a potential new generation antibacterial agent

• Main Authors: Norlin, Pauzi, Norashikin, Mat Zain, Rajaletchumy, Veloo Kutty, Hafizah, Ramli
• Format: Article
• Language: English
• Published: Elsevier 2020
• Subjects: T Technology (General); TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/29662/1/Antibacterial%20and%20antibiofilm%20properties%20of%20ZnO.pdf; http://umpir.ump.edu.my/id/eprint/29662/; https://doi.org/10.1016/j.matpr.2020.06.359; https://doi.org/10.1016/j.matpr.2020.06.359

This study aimed to investigate the antibacterial properties of gum arabic-ZnO nanoparticles. The antibacterial and antibiofilm activities of gum arabic-ZnO nanoparticles were evaluated against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) value of gum arabic-ZnO nanoparticles for S. aureus and E. coli was 31.25 lg/mL, 62.5 lg/mL and 62.5 lg /mL, 125 mg/mL respectively. At higher concentrations above 500 lg/mL, the percentage of toxicity to biofilm was observed more than 50% for both S. aureus and E. coli. Therefore gum arabic-ZnO nanoparticles are suggested as a natural new generation antibacterial agent.