Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes

• Main Authors: Ahmad Mahfuz, Gazali, Schroderus, Anna-Mari, Salonen, Kirsti Näntö, Rintamäki, Reeta, Pihlajamäki, Jussi, Knip, Mikael, Veijola, Riitta, Toppari, Jorma, Ilonen, Jorma, Kinnunen, Tuure
• Format: Article
• Language: English
• Published: Springer 2020
• Subjects: Q Science (General); QE Geology
• Online Access: http://umpir.ump.edu.my/id/eprint/29264/1/7.%20Mucosal-associated%20invariant%20T%20cell%20alterations%20during%20the%20development%20of%20human%20type%201%20diabetes.pdf; http://umpir.ump.edu.my/id/eprint/29264/; https://doi.org/10.1007/s00125-020-05257-7; https://doi.org/10.1007/s00125-020-05257-7

Aims/hypothesis Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognise derivatives of bacterial riboflavin metabolites presented by MHC-Ib-related protein 1 (MR1) molecules and are important effector cells for mucosal immunity. Their development can be influenced by the i...