Simultaneous analysis of drugs in forensic cases by liquid chromatography-high-resolution Orbitrap Mass Spectrometry

• Main Authors: Siti Umairah, Mokhtar, Kulsing, Chadin, Althakafy, Jalal T., Kotsos, Alex, Drummer, O. H., Marriott, P. J.
• Format: Article
• Language: English
• Published: Springer 2020
• Subjects: RM Therapeutics. Pharmacology; TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/27752/1/Simultaneous%20analysis%20of%20drugs%20in%20forensic%20cases%20by%20liquid%20.pdf; http://umpir.ump.edu.my/id/eprint/27752/; https://doi.org/10.1007/s10337-019-03814-w; https://doi.org/10.1007/s10337-019-03814-w

In the present study, liquid chromatography coupled to an Orbitrap mass spectrometer (HPLC–Q-Orbitrap MS) was used as an approach for identification and quantification of 113 drugs simultaneously in biological samples (whole blood/plasma/serum). Samples were prepared using liquid–liquid extraction c...