Evaluation of solvents’ effect on solubility, intermolecular interaction energies and habit of ascorbic acid crystals

• Main Authors: Shajaratul Jahriah, Hassan, Fatmawati, Adam, M. R., Abu Bakar, Siti Kholijah, Abdul Mudalip
• Format: Article
• Language: English
• Published: Elsevier 2019
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/21863/1/Evaluation%20of%20solvents%E2%80%99%20effect%20on%20solubility-INPRESS.pdf; http://umpir.ump.edu.my/id/eprint/21863/; https://doi.org/10.1016/j.jscs.2018.07.002; https://doi.org/10.1016/j.jscs.2018.07.002

Solubility of active pharmaceutical ingredient (API) in solvents is very important for drug development and manufacturing. Solubility data may provide further information such as thermochemical properties and intermolecular interactions that may lead to a better understanding of the formation of API...