Kinetics and Nucleation Mechanism of Carbamazepine–Saccharin Co-Crystals in Ethanol Solution

• Main Authors: Khairool Azizul, Mohammad, Syarifah, Abd Rahim, Mohd Rushdi, Abu Bakar
• Format: Article
• Language: English; English
• Published: Springer 2017
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/18680/1/Kinetics%20and%20Nucleation%20Mechanism%20of%20Carbamazepine%E2%80%93Saccharin%20Co-Crystals%20in%20Ethanol%20Solution.pdf; http://umpir.ump.edu.my/id/eprint/18680/6/Kinetics%20and%20Nucleation%20Mechanism%20of%20Carbamazepine%E2%80%93Saccharin%20Co-Crystals%20in%20Ethanol%20Solution%201.pdf; http://umpir.ump.edu.my/id/eprint/18680/; https://link.springer.com/article/10.1007/s10973-017-6483-1

This study aimed to investigate the metastable zone width (MSZW) and the nucleation order of carbamazepine–saccharin (CBZ–SAC) co-crystals via slow cooling crystallisation, to obtain the kinetic value using Kashchiev–Borissova–Hammond–Roberts (KBHR) technique and to deduce the induction time, the ra...