Bioassay Guided Isolation and Identification of a Cytotoxic Compound from Azadirachta indica Leaves

• Main Authors: Jessinta, Sandanasamy, Azhari, H. Nour, Hazrulrizawati, Hamid, Ahmad Ziad, Sulaiman, Saiful Nizam, Tajuddin, Nour, A. H.
• Format: Article
• Language: English
• Published: John Wiley & Sons, Inc. 2015
• Subjects: Q Science (General); TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/11331/1/Bioassay%20Guided%20Isolation%20and%20Identification%20of%20a%20Cytotoxic%20Compound%20from%20Azadirachta%20indica%20Leaves.pdf; http://umpir.ump.edu.my/id/eprint/11331/; http://onlinelibrary.wiley.com/doi/10.1002/jccs.201400461/abstract;jsessionid=B9D913E989CF4B333F0E947C4C4ED82D.f04t02?userIsAuthenticated=false&deniedAccessCustomisedMessage=

This study aimed to investigate the structural features of the isolated flavonol glycoside, which might behave as a cytotoxic compound. The hexane, chloroform, ethyl acetate, and aqueous fractions of an 80% methanol solution of Neem (Azadirachta indica) (Family: Meliaceae) leaves were subjected to a...