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Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)

The purpose of this research was to evaluate the brine shrimp lethality bioassay and antioxidant followed by antibacterial activity of the latex of Pterocarpus indicus. The latex showed high cytotoxic activity with LC5o value of 617.65 μg/mL compared to the cytotoxic activity of gallic acid of 451.2...

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Main Author: Mohamad Mahfuz Shaharudin
Format: Undergraduate Final Project Report
Published: 2013
Online Access:http://discol.umk.edu.my/id/eprint/5799/
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spelling my.umk.eprints.57992022-05-23T08:43:13Z http://discol.umk.edu.my/id/eprint/5799/ Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana) Mohamad Mahfuz Shaharudin The purpose of this research was to evaluate the brine shrimp lethality bioassay and antioxidant followed by antibacterial activity of the latex of Pterocarpus indicus. The latex showed high cytotoxic activity with LC5o value of 617.65 μg/mL compared to the cytotoxic activity of gallic acid of 451.2 μg/mL. The latex also showed significant DPPH free radical scavenging activity with IC₅₀ value of 0.1107 μg/mL as opposed to that of the scavenging effects of ascorbic acid of 4.5 pg μg/mL. Apart from that, the disc diffusion method showed that the latex of Pterocarpus indicus exhibit antibacterial activities against Staphylococcus aureus and Bacillus cereus with their inhibition zones ranging from 7.67 mm to 13.33 mm ± SD. However, it showed no inhibitory effect towards Salmonella sp, Pseudomonas sp and Escherichia coli. The data obtained in the present study suggests that the latex of Pterocarpus indicus have significant cytotoxic activity that can be used in cancer prevention, have potent antioxidant activity against free radicals and also possesses certain antibacterial activity. 2013 Undergraduate Final Project Report NonPeerReviewed Mohamad Mahfuz Shaharudin (2013) Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana). Undergraduate Final Project Report thesis, Faculty of Agro - Based Industry. (Submitted)
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description The purpose of this research was to evaluate the brine shrimp lethality bioassay and antioxidant followed by antibacterial activity of the latex of Pterocarpus indicus. The latex showed high cytotoxic activity with LC5o value of 617.65 μg/mL compared to the cytotoxic activity of gallic acid of 451.2 μg/mL. The latex also showed significant DPPH free radical scavenging activity with IC₅₀ value of 0.1107 μg/mL as opposed to that of the scavenging effects of ascorbic acid of 4.5 pg μg/mL. Apart from that, the disc diffusion method showed that the latex of Pterocarpus indicus exhibit antibacterial activities against Staphylococcus aureus and Bacillus cereus with their inhibition zones ranging from 7.67 mm to 13.33 mm ± SD. However, it showed no inhibitory effect towards Salmonella sp, Pseudomonas sp and Escherichia coli. The data obtained in the present study suggests that the latex of Pterocarpus indicus have significant cytotoxic activity that can be used in cancer prevention, have potent antioxidant activity against free radicals and also possesses certain antibacterial activity.
format Undergraduate Final Project Report
author Mohamad Mahfuz Shaharudin
spellingShingle Mohamad Mahfuz Shaharudin
Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
author_facet Mohamad Mahfuz Shaharudin
author_sort Mohamad Mahfuz Shaharudin
title Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
title_short Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
title_full Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
title_fullStr Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
title_full_unstemmed Antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (Angsana)
title_sort antibacterial, antioxidant and brine shrimp lethality activity of latex of pterocarpus indicus (angsana)
publishDate 2013
url http://discol.umk.edu.my/id/eprint/5799/
_version_ 1763303604864679936
score 13.211869

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