Characterisation of the human thyroid peroxidase gene mutations (S) in patients with congenital dyshormonogenetic hypothyroidism / Lee Ching Chin

• Main Author: Lee, Ching Chin
• Format: Thesis
• Published: 2013
• Subjects: R Medicine (General)
• Online Access: http://studentsrepo.um.edu.my/6116/1/Front_cover.pdf; http://studentsrepo.um.edu.my/6116/2/Title_Page_(i%2Dii).pdf; http://studentsrepo.um.edu.my/6116/3/Preface_(iii%2Dxxxvii)_new_(2).pdf; http://studentsrepo.um.edu.my/6116/4/Chapter_1_Introduction_(2%2D4).pdf; http://studentsrepo.um.edu.my/6116/5/Chapter_2_Literature_Review_(6%2D26).pdf; http://studentsrepo.um.edu.my/6116/6/Chapter_3_Materials_%26_Methods_(28%2D84).pdf; http://studentsrepo.um.edu.my/6116/7/Chapter_4_Results_(86%2D259).pdf; http://studentsrepo.um.edu.my/6116/8/Chapter_5_Discussion_(261%2D277).pdf; http://studentsrepo.um.edu.my/6116/9/Chapter_6_conclusion_and_suggestions_for_future_study_(279%2D280).pdf; http://studentsrepo.um.edu.my/6116/10/REFERENCES_(282%2D297).pdf; http://studentsrepo.um.edu.my/6116/11/APPENDICES_(299%2D320).pdf; http://studentsrepo.um.edu.my/6116/

Congenital hypothyroidism (CH) is a public health concern affecting 1 / 3000 - 4000 newborn babies. In reference to this, thyroid peroxidase (TPO) abnormality, typically inherited as autosomal recessive traits was found to be one of the causes of dyshormonogenetic CH. Our group had previously identi...