Prevalence of multidrug resistant Shigella isolated in Malaysia
Shigellosis, a disease caused by Shigella spp., is endemic in Malaysia. Its low infective dose and ease of spread through person-to-person transmission by the faecal-oral route make this infection difficult to control in outbreak situations. Antimicrobial therapy is recommended for shigellosis...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Icddr:b
2002
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/9970/1/Thong_2002.pdf http://eprints.um.edu.my/9970/ http://www.jhpn.net/index.php/jhpn/article/view/176/171 |
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| Summary: | Shigellosis, a disease caused by Shigella spp., is endemic
in Malaysia. Its low infective dose and ease of spread
through person-to-person transmission by the faecal-oral
route make this infection difficult to control in outbreak
situations. Antimicrobial therapy is recommended for
shigellosis because it can shorten the severity and
duration of illness, reduce shedding of the organism, and
prevent secondary complications and deaths. However,
due to the global emergence of drug resistance, the
choices of antimicrobial agents for empiric therapy for
shigellosis are now limited. Although antimicrobial
resistance of Shigella spp. is well-documented in many
countries (2-4), there is a lack of such documentation in
Malaysia. Hence, the study was undertaken to determine
the antimicrobial resistance patterns of the Malaysian
strains of Shigella spp. This study, to the best of our
knowledge, is the first report on the antimicrobial
resistance of Shigella spp. in Malaysia. |
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