Nosocomial outbreak of enterobacter gergoviae bacteremia in a neonatal intensive care unit

A nosocomial outbreak of bacteremia, caused by Enterobacter gergoviae infected 11 babies, nine of whom were premature, were investigated in the neonatal intensive care unit (NICU), of a general hospital in Johor Bahru, Malaysia. The strain that was isolated from the babies was also isolated from the...

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Bibliographic Details
Main Authors: Ganeswire, R., Thong, Kwai Lin, Puthucheary, S.D.
Format: Article
Language:English
Published: Elsevier 2002
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Online Access:http://eprints.um.edu.my/9953/1/Ganeswire_et_al.%2C_2002.pdf
http://eprints.um.edu.my/9953/
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Summary:A nosocomial outbreak of bacteremia, caused by Enterobacter gergoviae infected 11 babies, nine of whom were premature, were investigated in the neonatal intensive care unit (NICU), of a general hospital in Johor Bahru, Malaysia. The strain that was isolated from the babies was also isolated from the dextrose saline used for the dilution of parenteral antibiotics and from the hands of a healthcare worker on duty in the nursery. Pulsed-field gel electrophoresis (PFGE) of XbaI-digested chromosomal DNA confirmed a possible cross-contamination of parenteral dextrose saline and the healthcare worker. Prompt and effective control measures were initiated within NICU and the nosocomial infection of E. gergoviae was brought to an abrupt end. To the best of our knowledge, this is the first documented outbreak of E. gergoviae in the NICU in a hospital in the state of Johor, Malaysia.