Enhanced expression of a 35 kDa fragment of inter-alpha-trypsin inhibitor H4 in sera of healthy pregnant women and patients with hydatidiform mole

• Main Authors: Mohamed, E., Jayapalan, J.J., Abdul-Rahman, P.S., Omar, S.Z., Hashim, Onn Haji
• Format: Article
• Published: 2013
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/8571/; http://www.ncbi.nlm.nih.gov/pubmed/24252421

BACKGROUND: Accumulated data from previous studies appear to suggest a link between the overexpression of a 35 kDa fragment of serum inter-alpha-trypsin inhibitor H4 (ITIH4) with cancers that are associated with up-regulated levels of oestrogens. The truncated fragment was postulated to be a produc...