Chronic neutrophilic leukaemia.
Chronic neutrophilic leukaemia is a rare myeloproliferative disease characterised by splenomegaly, sustained neutrophilia, raised vitamin B12 level and absence of the Philadelphia chromosome. We report a 74-year-old man who presented first with Sweet's syndrome and subsequently leukocytosis. He...
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Stamford Publishing Pte Ltd / Singapore Medical Association
2007
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my.um.eprints.6242014-10-27T07:29:27Z http://eprints.um.edu.my/624/ Chronic neutrophilic leukaemia. Gan, G.G. Pasagna, J.F. Eow, G.I. Nadarajan, V.S. RC Internal medicine Chronic neutrophilic leukaemia is a rare myeloproliferative disease characterised by splenomegaly, sustained neutrophilia, raised vitamin B12 level and absence of the Philadelphia chromosome. We report a 74-year-old man who presented first with Sweet's syndrome and subsequently leukocytosis. He had splenomegaly, a raised vitamin B12 level, serum uric acid and neutrophil alkaline phosphatase score. Cytogenetic study of the marrow was normal and peripheral blood for BCR-ABL gene transcript was not detectable. He subsequently passed away with bronchopneumonia. Stamford Publishing Pte Ltd / Singapore Medical Association 2007-03 Article PeerReviewed Gan, G.G. and Pasagna, J.F. and Eow, G.I. and Nadarajan, V.S. (2007) Chronic neutrophilic leukaemia. Singapore Medical Journal, 48 (3). e74-6. ISSN 0037-5675 http://www.ncbi.nlm.nih.gov/pubmed/17342275 17342275 |
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RC Internal medicine Gan, G.G. Pasagna, J.F. Eow, G.I. Nadarajan, V.S. Chronic neutrophilic leukaemia. |
| description |
Chronic neutrophilic leukaemia is a rare myeloproliferative disease characterised by splenomegaly, sustained neutrophilia, raised vitamin B12 level and absence of the Philadelphia chromosome. We report a 74-year-old man who presented first with Sweet's syndrome and subsequently leukocytosis. He had splenomegaly, a raised vitamin B12 level, serum uric acid and neutrophil alkaline phosphatase score. Cytogenetic study of the marrow was normal and peripheral blood for BCR-ABL gene transcript was not detectable. He subsequently passed away with bronchopneumonia. |
| format |
Article |
| author |
Gan, G.G. Pasagna, J.F. Eow, G.I. Nadarajan, V.S. |
| author_facet |
Gan, G.G. Pasagna, J.F. Eow, G.I. Nadarajan, V.S. |
| author_sort |
Gan, G.G. |
| title |
Chronic neutrophilic leukaemia. |
| title_short |
Chronic neutrophilic leukaemia. |
| title_full |
Chronic neutrophilic leukaemia. |
| title_fullStr |
Chronic neutrophilic leukaemia. |
| title_full_unstemmed |
Chronic neutrophilic leukaemia. |
| title_sort |
chronic neutrophilic leukaemia. |
| publisher |
Stamford Publishing Pte Ltd / Singapore Medical Association |
| publishDate |
2007 |
| url |
http://eprints.um.edu.my/624/ http://www.ncbi.nlm.nih.gov/pubmed/17342275 |
| _version_ |
1643686595774119936 |
| score |
13.160551 |