Computational studies on the cognate and non-cognate aminoacyl-tRNAs

• Main Authors: Monajemi, H., Abdullah, W.A.T.W., Zain, Sharifuddin Md
• Format: Article
• Published: Faculty of Science, University of Malaya 2011
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/6068/; http://www.scopus.com/inward/record.url?eid=2-s2.0-80054122918&partnerID=40&md5=cf93825b877dcc9e9576c81900f3d45d

Although kinetic proofreading plays a major role in the fidelity of protein synthesis, it only includes the codon-anticodon interaction without considering the amino acid side chain. It is not known whether the ribosome has a specific interaction with the amino acid side chain or if the correctly ch...