The role of initiator tRNA I met in fidelity of initiation of protein synthesis

• Main Authors: Monajemi, H., Abdullah, W.A.T.W., Zain, Sharifuddin Md, Daud, M.N., Omar, N.Y.M.
• Format: Article
• Published: 2011
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/6065/; http://www.scopus.com/inward/record.url?eid=2-s2.0-80052659641&partnerID=40&md5=c16d197b9e529fd2050a2448dd1b67a2

The proper arrangement of amino acids in a protein determines its proper function, which is vital for the cellular metabolism. This indicates that the process of peptide bond formation requires high fidelity. One of the most important processes for this fidelity is kinetic proofreading. As biochemic...