Ultrasensitive detection of cancer biomarkers in the clinic by use of a nanostructured microfluidic array

• Main Authors: Malhotra, R., Patel, V., Chikkaveeraiah, B.V., Munge, B.S., Cheong, S.C., Zain, R.B., Abraham, M.T., Dey, D.K., Gutkind, J.S., Rusling, J.F.
• Format: Article
• Language: English
• Published: 2012
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/6027/1/Ultrasensitive_Detection_of_Cancer_Biomarkers_in_the_Clinic_by_Use_of_a_Nanostructured_Microfluidic_Array.pdf; http://eprints.um.edu.my/6027/; http://www.ncbi.nlm.nih.gov/pubmed/22697359

Multiplexed biomarker protein detection holds unrealized promise for clinical cancer diagnostics due to lack of suitable measurement devices and lack of rigorously validated protein panels. Here we report an ultrasensitive electrochemical microfluidic array optimized to measure a four-protein panel...