Mechanistic studies of the anti-ulcerogenic activity and acute toxicity evaluation of dichlorido-copper(II)-4-(2-5-Bromobenzylideneamino)ethyl) piperazin-1-ium phenolate complex against ethanol-induced gastric injury in rats

• Main Authors: Salga, M.S., Hadi, A.H.A., Hussain, P.D., Abdelwahab, S.I., Abdullah, M.A., Ali, Hapipah Mohd
• Format: Article
• Language: English
• Published: 2011
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/5203/1/Salga-2011-Mechanistic_Studies.pdf; http://eprints.um.edu.my/5203/; http://www.mdpi.com/1420-3049/16/10/8654

The compound dichlorido-copper(II)-4-(2-5-bromobenzylideneamino)ethyl) piperazin-1-ium phenolate (CuLBS) was synthesized, characterized and screened for acute toxicity and protective activity against ethanol-induced gastric mucosal injury in rats. Gross microscopic lesions, biochemical and immunolog...