Synthesis,characterization, acetylcholinesterase inhibition, molecular modeling and antioxidant activities of some novel schiff bases derived from 1-(2-ketoiminoethyl)piperazines

• Main Authors: Salga, S.M., Hadi, A.H.A., Sukumaran, S.D., Buckle, M.J.C., Wai, L.K., Abdelwahab, S.I., Abdullah, M.A., Ali, Hapipah Mohd
• Format: Article
• Language: English
• Published: 2011
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/5195/1/Salga-2011-Synthesis%2C_Character.pdf; http://eprints.um.edu.my/5195/; http://www.mdpi.com/1420-3049/16/11/9316/pdf

Some novel Schiff bases derived from 1-(2-ketoiminoethyl)piperazines were synthesized and characterized by mass spectroscopy, FTIR, UV-Visible, (1)H and (13)C-NMR. The compounds were tested for inhibitory activities on human acetylcholinesterase (hAChE), antioxidant activities, acute oral toxicity a...