Anti-proliferative effects of calcitriol on endothelial cells derived from two different microenvironments

• Main Authors: Chung, I., Yu, W.D., Karpf, A.R., Flynn, G., Bernardi, R.J., Modzelewski, R.A., Johnson, C.S., Trump, D.L.
• Format: Article
• Language: English
• Published: 2007
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/5034/1/Chung-2007-Anti-proliferative_e.pdf; http://eprints.um.edu.my/5034/

Calcitriol (1,25-dihydroxycholecalciferol), the active form of Vitamin D, is anti-proliferative in tumor cells and tumor-derived endothelial cells (TDEC). However, endothelial cells isolated from normal tissues as cell lines or freshly isolated cells or from implanted Matrigel plugs (MDEC) are relat...