Structural insights and cytotoxicity evaluation of benz[e]indole pyrazolyl-substituted amides

• Main Authors: Ramle, Abdul Qaiyum, Chan, Nadia Nabihah Mohd Yusof, Ng, Min Phin, Tan, Chun Hoe, Sim, Kae Shin, Tiekink, Edward R. T., Fei, Chee Chin
• 格式: Article
• 出版: Kluwer (now part of Springer) 2024
• 主題: QD Chemistry; QH Natural history
• 在線閱讀: http://eprints.um.edu.my/47168/; https://doi.org/10.1007/s11030-023-10662-2

Five new compounds of benze]indole pyrazolyl-substituted amides (2a-e) were synthesised in low to good yields via the direct amide-coupling reaction between a pyrazolyl derivative containing a carboxylic acid and several amine substrates. The molecular structures were determined by various spectrosc...