Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry

AimsHeart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of Malaysian patients with HF and identify areas for improvemen...

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Main Authors: Ahmad, Wan Azman Wan, Ghapar, Abdul Kahar Abdul, Abidin, Hafisyatul Aiza Zainal, Karthikesan, Dharmaraj, Ross, Noel Thomas, Kader, Muhamad Ali S. K. Abdul, Loch, Alexander, Mahendran, Kauthaman, Ramli, Ahmad Wazi, Ong, Tiong Kiam, Amin, Nor Hanim Mohd, Lee, Chuey Yan, Hassan, Hamat Hamdi Che, Abidin, Siti Khairani Zainal, Liew, Houng Bang, Ho, Wing Sze, Ghazi, Azmee Mohd
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Published: Wiley 2024
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Online Access:http://eprints.um.edu.my/45933/
https://doi.org/10.1002/ehf2.14608
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spelling my.um.eprints.459332024-11-14T05:35:57Z http://eprints.um.edu.my/45933/ Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry Ahmad, Wan Azman Wan Ghapar, Abdul Kahar Abdul Abidin, Hafisyatul Aiza Zainal Karthikesan, Dharmaraj Ross, Noel Thomas Kader, Muhamad Ali S. K. Abdul Loch, Alexander Mahendran, Kauthaman Ramli, Ahmad Wazi Ong, Tiong Kiam Amin, Nor Hanim Mohd Lee, Chuey Yan Hassan, Hamat Hamdi Che Abidin, Siti Khairani Zainal Liew, Houng Bang Ho, Wing Sze Ghazi, Azmee Mohd R Medicine (General) AimsHeart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of Malaysian patients with HF and identify areas for improvement within the national HF services.Methods and resultsThe MY-HF Registry is a 3-year prospective, observational study comprising 2717 Malaysian patients admitted for acute HF. We report the description of baseline data at admission and outcomes of index hospitalization of these patients. The mean age was 60.2 +/- 13.6 years, 66.8% were male, and 34.3% had de novo HF. Collectively, 55.7% of patients presented with New York Heart Association (NYHA) Class III or IV; ischaemic heart disease was the most frequent aetiology (63.2%). Most admissions (87.3%) occurred via the emergency department, with 13.7% of patients requiring intensive care, and of these, 21.8% needed intubation. The proportion of patients receiving guideline-directed medical therapy increased at discharge (84.2% vs. 93.6%). The median length of stay (LOS) was 5 days, and in-hospital mortality was 2.9%. Predictors of LOS and/or in-hospital mortality were age, NYHA class, estimated glomerular filtration rate, and comorbid anaemia. LOS and in-hospital mortality were similar regardless of ejection fraction.ConclusionsThe MY-HF Registry showed that the HF population in Malaysia is younger, predominantly male, and ischaemic-driven and has good prospects with hospitalization for optimization of treatment. These findings suggest a need to reassess current clinical practice and guide resource allocation to improve patient outcomes. Wiley 2024-04 Article PeerReviewed Ahmad, Wan Azman Wan and Ghapar, Abdul Kahar Abdul and Abidin, Hafisyatul Aiza Zainal and Karthikesan, Dharmaraj and Ross, Noel Thomas and Kader, Muhamad Ali S. K. Abdul and Loch, Alexander and Mahendran, Kauthaman and Ramli, Ahmad Wazi and Ong, Tiong Kiam and Amin, Nor Hanim Mohd and Lee, Chuey Yan and Hassan, Hamat Hamdi Che and Abidin, Siti Khairani Zainal and Liew, Houng Bang and Ho, Wing Sze and Ghazi, Azmee Mohd (2024) Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry. ESC Heart Failure, 11 (2). pp. 727-736. ISSN 2055-5822, DOI https://doi.org/10.1002/ehf2.14608 <https://doi.org/10.1002/ehf2.14608>. https://doi.org/10.1002/ehf2.14608 10.1002/ehf2.14608
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Ahmad, Wan Azman Wan
Ghapar, Abdul Kahar Abdul
Abidin, Hafisyatul Aiza Zainal
Karthikesan, Dharmaraj
Ross, Noel Thomas
Kader, Muhamad Ali S. K. Abdul
Loch, Alexander
Mahendran, Kauthaman
Ramli, Ahmad Wazi
Ong, Tiong Kiam
Amin, Nor Hanim Mohd
Lee, Chuey Yan
Hassan, Hamat Hamdi Che
Abidin, Siti Khairani Zainal
Liew, Houng Bang
Ho, Wing Sze
Ghazi, Azmee Mohd
Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
description AimsHeart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of Malaysian patients with HF and identify areas for improvement within the national HF services.Methods and resultsThe MY-HF Registry is a 3-year prospective, observational study comprising 2717 Malaysian patients admitted for acute HF. We report the description of baseline data at admission and outcomes of index hospitalization of these patients. The mean age was 60.2 +/- 13.6 years, 66.8% were male, and 34.3% had de novo HF. Collectively, 55.7% of patients presented with New York Heart Association (NYHA) Class III or IV; ischaemic heart disease was the most frequent aetiology (63.2%). Most admissions (87.3%) occurred via the emergency department, with 13.7% of patients requiring intensive care, and of these, 21.8% needed intubation. The proportion of patients receiving guideline-directed medical therapy increased at discharge (84.2% vs. 93.6%). The median length of stay (LOS) was 5 days, and in-hospital mortality was 2.9%. Predictors of LOS and/or in-hospital mortality were age, NYHA class, estimated glomerular filtration rate, and comorbid anaemia. LOS and in-hospital mortality were similar regardless of ejection fraction.ConclusionsThe MY-HF Registry showed that the HF population in Malaysia is younger, predominantly male, and ischaemic-driven and has good prospects with hospitalization for optimization of treatment. These findings suggest a need to reassess current clinical practice and guide resource allocation to improve patient outcomes.
format Article
author Ahmad, Wan Azman Wan
Ghapar, Abdul Kahar Abdul
Abidin, Hafisyatul Aiza Zainal
Karthikesan, Dharmaraj
Ross, Noel Thomas
Kader, Muhamad Ali S. K. Abdul
Loch, Alexander
Mahendran, Kauthaman
Ramli, Ahmad Wazi
Ong, Tiong Kiam
Amin, Nor Hanim Mohd
Lee, Chuey Yan
Hassan, Hamat Hamdi Che
Abidin, Siti Khairani Zainal
Liew, Houng Bang
Ho, Wing Sze
Ghazi, Azmee Mohd
author_facet Ahmad, Wan Azman Wan
Ghapar, Abdul Kahar Abdul
Abidin, Hafisyatul Aiza Zainal
Karthikesan, Dharmaraj
Ross, Noel Thomas
Kader, Muhamad Ali S. K. Abdul
Loch, Alexander
Mahendran, Kauthaman
Ramli, Ahmad Wazi
Ong, Tiong Kiam
Amin, Nor Hanim Mohd
Lee, Chuey Yan
Hassan, Hamat Hamdi Che
Abidin, Siti Khairani Zainal
Liew, Houng Bang
Ho, Wing Sze
Ghazi, Azmee Mohd
author_sort Ahmad, Wan Azman Wan
title Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
title_short Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
title_full Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
title_fullStr Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
title_full_unstemmed Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
title_sort characteristics of patients admitted with heart failure: insights from the first malaysian heart failure registry
publisher Wiley
publishDate 2024
url http://eprints.um.edu.my/45933/
https://doi.org/10.1002/ehf2.14608
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score 13.214268