Biocatalytic Generation of o-Quinone Imines in the Synthesis of 1,4-Benzoxazines and Its Comparative Green Chemistry Metrics
1,4-Benzoxazines are important motifs in many pharmaceuticals and can be formed by a reaction sequence involving the oxidation of o-aminophenols to their corresponding quinone imine followed by an in situ inverse electron demand Diels-Alder (IEDDA) cycloaddition with a suitable dienophile. Reported...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2024
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/45667/ https://doi.org/10.1021/acssuschemeng.3c06758 |
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