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Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.

We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing ana...

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Main Authors: Ho, Siaw Eng, Subramaniam, Geetha, Palasubramaniam, Selvi, Navaratnam, Parasakthi
Format: Article
Published: American Society for Microbiology 2002
Subjects:
R Medicine (General)
Online Access:http://eprints.um.edu.my/452/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128803/?tool=pubmed
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spelling my.um.eprints.4522019-02-07T07:15:15Z http://eprints.um.edu.my/452/ Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Ho, Siaw Eng Subramaniam, Geetha Palasubramaniam, Selvi Navaratnam, Parasakthi R Medicine (General) We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant. American Society for Microbiology 2002-10 Article PeerReviewed Ho, Siaw Eng and Subramaniam, Geetha and Palasubramaniam, Selvi and Navaratnam, Parasakthi (2002) Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Antimicrobial Agents and Chemotherapy, 46 (10). pp. 3286-7. ISSN 0066-4804 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128803/?tool=pubmed 12234862
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Ho, Siaw Eng
Subramaniam, Geetha
Palasubramaniam, Selvi
Navaratnam, Parasakthi
Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
description We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.
format Article
author Ho, Siaw Eng
Subramaniam, Geetha
Palasubramaniam, Selvi
Navaratnam, Parasakthi
author_facet Ho, Siaw Eng
Subramaniam, Geetha
Palasubramaniam, Selvi
Navaratnam, Parasakthi
author_sort Ho, Siaw Eng
title Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
title_short Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
title_full Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
title_fullStr Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
title_full_unstemmed Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
title_sort carbapenem-resistant pseudomonas aeruginosa in malaysia producing imp-7 beta-lactamase.
publisher American Society for Microbiology
publishDate 2002
url http://eprints.um.edu.my/452/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128803/?tool=pubmed
_version_ 1643686573069303808
score 13.209306

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