Neurophysiological and imaging biomarkers of lower motor neuron dysfunction in motor neuron diseases/amyotrophic lateral sclerosis: IFCN handbook chapter

• Main Authors: Lin, Cindy Shin-Yi, Howells, James, Rutkove, Seward, Nandedkar, Sanjeev, Neuwirth, Christoph, Noto, Yu-ichi, Shahrizaila, Nortina, Whittaker, Roger G., Bostock, Hugh, Burke, David, Tankisi, Hatice
• Format: Article
• Published: Elsevier 2024
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/45187/; https://doi.org/10.1016/j.clinph.2024.03.015

This chapter discusses comprehensive neurophysiological biomarkers utilised in motor neuron disease (MND) and, in particular, its commonest form, amyotrophic lateral sclerosis (ALS). These encompass the conventional techniques including nerve conduction studies (NCS), needle and high-density surface...