Nanofiber/hydrogel composite scaffold incorporated by silicon nanoparticles for sustained delivery of osteogenic factor: in vitro study

• Main Authors: Oustadi, Fereshteh, Imani, Rana, Nazarpak, Masoumeh Haghbin, Sharifi, Ali Mohammad, McInnes, Steven J. P.
• Format: Article
• Published: TAYLOR & FRANCIS AS 2024
• Subjects: RZ Other systems of medicine
• Online Access: http://eprints.um.edu.my/44335/; https://doi.org/10.1080/00914037.2022.2147176

Utilizing bone scaffolds for osteogenic factors delivery has the vital advantage of faster and more efficient tissue regeneration. In this study, rosuvastatin calcium is loaded into the silicon nanoparticles and then incorporated into PLLA nanofibers followed by immersion into the gelatin hydrogel....