Vasorelaxant effect of a phenylethylamine analogue based on schwarzinicine A an alkaloid isolated from the leaves of Ficus schwarzii

• Main Authors: Govindaraju, Kayatri, Mak, Yin Ying, Lee, Fong Kai, Bauer, Claudia C., Lim, Kuan Hon, Bon, Robin S., Kong, Cin, Then, Sue Mian, Ting, Kang Nee
• Format: Article
• Published: Elsevier 2024
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/44247/; https://doi.org/10.1016/j.phytol.2023.11.007

N-Phenethyl-1-phenyl-pentan-3-amine (1) is a new compound synthesised as a simplified analogue of schwarzinicine A (2), a natural compound extracted from Ficus schwarzii. Compound 1 differs from compound 2 due to its structural simplification, featuring two phenyl rings without methoxy substitution,...