Cover Image

Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?

Percutaneous coronary intervention (PCI) has been established as a definitive method to treat obstructive coronary artery disease. The procedure on its own, however, is insufficient to ensure optimal longterm patient outcomes as it is also necessary to achieve good control of relevant risk factors....

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Zhen-Vin, Lam, Ho
Format: Article
Published: Europa Group 2022
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/43936/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.um.eprints.43936
record_format eprints
spelling my.um.eprints.439362024-01-29T03:51:40Z http://eprints.um.edu.my/43936/ Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how? Lee, Zhen-Vin Lam, Ho R Medicine Percutaneous coronary intervention (PCI) has been established as a definitive method to treat obstructive coronary artery disease. The procedure on its own, however, is insufficient to ensure optimal longterm patient outcomes as it is also necessary to achieve good control of relevant risk factors. The process of atherosclerosis as a result of dyslipidaemia is a risk continuum and secondary preventive measures for patients who have undergone PCI are of paramount importance to mitigate the risk of procedural failure and further cardiovascular events. This review aims to provide an overview of the landscape of lipidlowering therapy for the purpose of secondary prevention by summarising recommendations derived from contemporary guidelines and highlighting the rationale and evidence behind the three main lipid-lowering therapies, namely statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. It also provides insights into real-world challenges and issues surrounding secondary prevention of dyslipidaemia such as suboptimal lipid goal attainment and nonadherence, and assesses the possible methods to overcome them. © Europa Digital & Publishing 2022. Europa Group 2022 Article PeerReviewed Lee, Zhen-Vin and Lam, Ho (2022) Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how? AsiaIntervention, 8 (1). 24 – 31. ISSN 2426-3958, DOI https://doi.org/10.4244/AIJ-D-22-00005 <https://doi.org/10.4244/AIJ-D-22-00005>. 10.4244/AIJ-D-22-00005
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Lee, Zhen-Vin
Lam, Ho
Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
description Percutaneous coronary intervention (PCI) has been established as a definitive method to treat obstructive coronary artery disease. The procedure on its own, however, is insufficient to ensure optimal longterm patient outcomes as it is also necessary to achieve good control of relevant risk factors. The process of atherosclerosis as a result of dyslipidaemia is a risk continuum and secondary preventive measures for patients who have undergone PCI are of paramount importance to mitigate the risk of procedural failure and further cardiovascular events. This review aims to provide an overview of the landscape of lipidlowering therapy for the purpose of secondary prevention by summarising recommendations derived from contemporary guidelines and highlighting the rationale and evidence behind the three main lipid-lowering therapies, namely statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. It also provides insights into real-world challenges and issues surrounding secondary prevention of dyslipidaemia such as suboptimal lipid goal attainment and nonadherence, and assesses the possible methods to overcome them. © Europa Digital & Publishing 2022.
format Article
author Lee, Zhen-Vin
Lam, Ho
author_facet Lee, Zhen-Vin
Lam, Ho
author_sort Lee, Zhen-Vin
title Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
title_short Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
title_full Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
title_fullStr Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
title_full_unstemmed Aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
title_sort aggressive lipid-lowering therapy after percutaneous coronary intervention-for whom and how?
publisher Europa Group
publishDate 2022
url http://eprints.um.edu.my/43936/
_version_ 1789424631551098880
score 13.211869

Similar Items