Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial

Background and Aims: Postoperative sore throat (POST) is an undesirable event reported in up to 62 of patients receiving general anaesthesia (GA). The incidence of POST following GA using a supraglottic airway device (SAD) is approximately 50, with symptoms persisting up to 48 h. We examined the rol...

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Main Authors: Sundaraj, Sebastian, Shariffuddin, Ina Ismiarti, Chaw, Sook Hui, Wan Zakaria, Wan, Shan Ng, Kevin, Ruslan, Shairil
Format: Article
Published: Medknow Publications 2022
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Online Access:http://eprints.um.edu.my/43782/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135489930&doi=10.4103%2fija.ija_809_21&partnerID=40&md5=4e78a47cc896c814772509835ee3e12f
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Summary:Background and Aims: Postoperative sore throat (POST) is an undesirable event reported in up to 62 of patients receiving general anaesthesia (GA). The incidence of POST following GA using a supraglottic airway device (SAD) is approximately 50, with symptoms persisting up to 48 h. We examined the role of preoperative lozenges containing amylmetacresol and dichlorobenzyl alcohol (AMC/DCBA) with lignocaine (Strepsils ® Max Plus) in reducing the incidence and intensity of POST following GA using SAD. Methods: We conducted a prospective, double-blinded, randomised, placebo-controlled trial involving 88 adults receiving GA for elective surgery using SAD not exceeding 2 h. Patients received either Strepsils Max Plus (Strepsils-LA group) or a placebo before induction of GA. The incidence and intensity of sore throat, dysphagia and dysphonia was measured using the Verbal Rating Scale at 30 min (early) and at 24 h (late) after removal of SAD. Results: Overall POST incidence was lower in the Strepsils-LA group (27.7 ver