Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report
Red eye is common in our daily practice. It ranges from non-inflammatory to inflammatory causes. An extended course of disease should prompt suspicion and the possibility of diagnosis revision. A prolonged conjunctivitis mimicking nodular episcleritis can be presented as a manifestation of granuloma...
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my.um.eprints.433392023-12-03T01:27:17Z http://eprints.um.edu.my/43339/ Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report Lee, Hong Nien Subrayan, Visvaraja RE Ophthalmology Red eye is common in our daily practice. It ranges from non-inflammatory to inflammatory causes. An extended course of disease should prompt suspicion and the possibility of diagnosis revision. A prolonged conjunctivitis mimicking nodular episcleritis can be presented as a manifestation of granulomatosis with polyangiitis (GPA). A 57-year-old woman complained of eye redness and tearing for two weeks which partially resolved with antibiotics. She was subsequently commenced on topical and oral non-steroidal anti-inflammatory drugs (NSAIDs) and topical anti-allergic. However, in the following reviews she developed cornea thinning and her systemic examination revealed an injected uvula with absence of upper respiratory tract infection. She was investigated for connective tissue disease and found to have raised anti-inflammatory markers and her antinuclear antibody and C-ANCA tests were positive. She was diagnosed with GPA. Her conditions improved followed by the commencement of topical corticosteroid with high dose of systemic corticosteroid, which followed by a tapering regime with oral corticosteroid. Although red eye is common, it is associated with a variety of diseases. GPA manifestation can be as subtle as a red eye. Any prolonged partially treated red eye should prompt suspicion of a more sinister cause. Sensitive detection of other subtle systemic signs is very important. © Annals of Eye Science. All rights reserved. AME Publishing Company 2022 Article PeerReviewed Lee, Hong Nien and Subrayan, Visvaraja (2022) Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report. Annals of Eye Science, 7. ISSN 2520-4122, DOI https://doi.org/10.21037/aes-21-32 <https://doi.org/10.21037/aes-21-32>. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127655333&doi=10.21037%2faes-21-32&partnerID=40&md5=fbee91bb12d29a9f6242a7d29a102330 10.21037/aes-21-32 |
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Red eye is common in our daily practice. It ranges from non-inflammatory to inflammatory causes. An extended course of disease should prompt suspicion and the possibility of diagnosis revision. A prolonged conjunctivitis mimicking nodular episcleritis can be presented as a manifestation of granulomatosis with polyangiitis (GPA). A 57-year-old woman complained of eye redness and tearing for two weeks which partially resolved with antibiotics. She was subsequently commenced on topical and oral non-steroidal anti-inflammatory drugs (NSAIDs) and topical anti-allergic. However, in the following reviews she developed cornea thinning and her systemic examination revealed an injected uvula with absence of upper respiratory tract infection. She was investigated for connective tissue disease and found to have raised anti-inflammatory markers and her antinuclear antibody and C-ANCA tests were positive. She was diagnosed with GPA. Her conditions improved followed by the commencement of topical corticosteroid with high dose of systemic corticosteroid, which followed by a tapering regime with oral corticosteroid. Although red eye is common, it is associated with a variety of diseases. GPA manifestation can be as subtle as a red eye. Any prolonged partially treated red eye should prompt suspicion of a more sinister cause. Sensitive detection of other subtle systemic signs is very important. © Annals of Eye Science. All rights reserved. |
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Article |
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Lee, Hong Nien Subrayan, Visvaraja |
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Lee, Hong Nien Subrayan, Visvaraja |
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Lee, Hong Nien |
title |
Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report |
title_short |
Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report |
title_full |
Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report |
title_fullStr |
Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report |
title_full_unstemmed |
Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: A case report |
title_sort |
prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis: a case report |
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AME Publishing Company |
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2022 |
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http://eprints.um.edu.my/43339/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127655333&doi=10.21037%2faes-21-32&partnerID=40&md5=fbee91bb12d29a9f6242a7d29a102330 |
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