Olaparib Maintenance Monotherapy in Asian Patients with Platinum-Sensitive Relapsed Ovarian Cancer: Phase III Trial (L-MOCA)

• Main Authors: Gao, Qinglei, Zhu, Jianqing, Zhao, Weidong, Huang, Yi, An, Ruifang, Zheng, Hong, Qu, Pengpeng, Wang, Li, Zhou, Qi, Wang, Danbo, Lou, Ge, Wang, Jing, Wang, Ke, Low, John, Kong, Beihua, Abdul Malik, Rozita, Sen, Lim Chun, Yin, Rutie, Xie, Xing, Liu, Jihong, Sun, Wei, Su, Jingya, Zhang, Chunyi, Zang, Rongyu, Ma, Ding
• Format: Article
• Published: Amer Assoc Cancer Research 2022
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/42135/

Purpose: In patients with platinum-sensitive relapsed (PSR) ovarian cancer, olaparib maintenance monotherapy significantly improves progression-free survival (PFS) versus placebo. However, evidence in the Asian population is lacking. This is the first study to evaluate olaparib efficacy and tolerabi...