New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus

• Main Authors: Norpi, Abdin Shakirin Mohamad, Nordin, Muhammad Luqman, Ahmad, Nuraziemah, Katas, Haliza, Ahmad Fuaad, Abdullah Al-Hadi, Sukri, Asif, Marasini, Nirmal, Azmi, Fazren
• Format: Article
• Published: SHENYANG PHARMACEUTICAL UNIV 2022
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://eprints.um.edu.my/41998/

An effective vaccine against group A streptococcus (GAS) is highly desirable for definitive control of GAS infections. In the present study, two variants of amphiphilic chitosan nanoparticles-based GAS vaccines were developed. The vaccines were primarily composed of encapsulated KLH protein (a sourc...