Antibody-dependent cellular phagocytosis of tropomyosin receptor kinase C (TrkC) expressing cancer cells for targeted immunotherapy

• Main Authors: Lai, Phei San, Usama, Syed Muhammad, Kiew, Lik Voon, Lee, Hong Boon, Chung, Lip Yong, Burgess, Kevin, Kue, Chin Siang
• Format: Article
• Published: SPRINGER 2022
• Subjects: RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://eprints.um.edu.my/41765/

Conventional cancer therapies such as chemotherapy are non-selective and induce immune system anergy, which lead to serious side effects and tumor relapse. It is a challenge to prime the body's immune system in the cancer-bearing subject to produce cancer antigen-targeting antibodies, as most t...