Hydrogels responsive towards important biological-based stimuli

• Main Authors: Ong, Chong-Boon, Annuar, Mohamad Suffian Mohamad
• Format: Article
• Published: Springer 2022
• Subjects: QC Physics; QD Chemistry
• Online Access: http://eprints.um.edu.my/41468/

Bioresponsive hydrogels are polymers with the ability to absorb a large volume of water and able to response towards specific stimuli e.g., biomolecules ranging from enzymes, antigens, nucleic acids to glucose. The biorecognition events trigger changes in the form of macroscopic responses such as swelling or deswelling, degradation, or optical density variation. Surveying the literature spanning the last decade until recently, the review highlights biomedical applications for bioresponsive hydrogels, particularly in diagnostics, drug delivery, and tissue regeneration/wound healing, with responses directed towards enzyme, nucleic acid, and glucose.