Deciphering the structural and functional impact of Q657L mutation in NLRC4 using computational methods

The NLR family caspase recruitment domain-containing protein 4 (NLRC4) inflammasome regulates the inflammatory response. Upregulation of NLRC4 inflammasome has been associated with bacterial infections, cancers, and autoinflammatory disorders (AIDs). The Q657L mutation in the NLRC4 causes AID. Howev...

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Bibliographic Details
Main Authors: Chear, Chai Teng, Ripen, Adiratna Mat, Mohamad, Saharuddin
Format: Article
Published: Taylor & Francis 2022
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Online Access:http://eprints.um.edu.my/41448/
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