Inhibition of endoplasmic reticulum stress improves acetylcholine-mediated relaxation in the aorta of type-2 diabetic rats

• Main Authors: Mustapha, Sagir, Azemi, Ahmad Khusairi, Ahmad, Wan Amir Nizam Wan, Rasool, Aida Hanum Ghulam, Mustafa, Mohd Rais, Mokhtar, Siti Safiah
• Format: Article
• Published: MDPI 2022
• Subjects: QD Chemistry; R Medicine
• Online Access: http://eprints.um.edu.my/41388/

Endoplasmic reticulum (ER) stress contributes to insulin resistance and macro- and microvascular complications associated with diabetes. This study aimed to evaluate the effect of ER stress inhibition on endothelial function in the aorta of type-2 diabetic rats. Type-2 diabetes was developed in male...