CRISPRi-mediated down-regulation of the Cinnamate-4-Hydroxylase (C4H) gene enhances the flavonoid biosynthesis in nicotiana tabacum

• Main Authors: Karlson, Chou Khai Soong, Noor, Siti Nurfadhlina Mohd, Khalid, Norzulaani, Tan, Boon Chin
• Format: Article
• Published: MDPI 2022
• Subjects: GE Environmental Sciences; QK Botany
• Online Access: http://eprints.um.edu.my/41379/

Flavonoids are natural compounds in plants. They play a critical role in plant growth and pathogen defense. Due to their health benefits, flavonoids have gained much attention as potent therapeutic agents. However, the low abundance of flavonoids in nature has limited their exploitation. Hence, this...