Combined use of Wild-Type HBV precore and high herum iron marker as a potential tool for the prediction of cirrhosis in chronic Hepatitis B infection

• Main Authors: Chook, J.B., Ngeow, Y.F., Yap, S.F., Tan, T.C., Mohamed, R.
• Format: Article
• Language: English
• Published: 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/4029/1/Chook-2011-Combined_Use_of_Wild.pdf; http://eprints.um.edu.my/4029/; http://onlinelibrary.wiley.com/store/10.1002/jmv.22016/asset/22016_ftp.pdf?v=1&t=h8az0yby&s=58b2f4f0ee673c04a7a6dd55fedc1e602db2264a

Hepatitis B virus (HBV) and high liver iron deposits have both been associated with the development of cirrhosis. Among HBV factors, genotype and mutations in the basal core promoter (BCP) and precore regions have been most frequently studied but the evidence for a positive association with cirrhosi...