The chemotherapeutic efficacy of hyaluronic acid coated polymeric nanoparticles against breast cancer metastasis in female NCr-Nu/Nu nude mice

• Main Authors: Almoustafa, Hassan A., Alshawsh, Mohammed Abdullah, Al-Suede, Fouad Saleih R., Alshehade, Salah Abdulrazak, Majid, Amin Malik Shah Abdul, Chik, Zamri
• Format: Article
• Published: MDPI 2023
• Subjects: Q Science (General); R Medicine
• Online Access: http://eprints.um.edu.my/38940/

Polyethylene glycol (PEG) coated Poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) for cancer treatment are biocompatible, nonimmunogenic and accumulate in tumour sites due to the enhanced permeability and retention (EPR). Doxorubicin (DOX) is a potent but cardiotoxic anticancer agent. Hyaluro...