Prospective features of functional 2D nanomaterial graphene oxide in the wound healing process

• Main Authors: Chandrasekaran, Rajkuberan, Krishnan, Muthukumar, Bupesh, Giridharan, Chacko, Sonu, Gawade, Omkar, Hasan, Sheik, George, Evelin, Vijayakumar, Tharumasivam Siva, Sundaram, Meenakshi, Sagadevan, Suresh
• Format: Article
• Published: Elsevier 2023
• Subjects: T Technology (General); TP Chemical technology
• Online Access: http://eprints.um.edu.my/38436/

The treatment of chronic and non-chronic wounds is becoming a major challenge for clinicians due to various intrinsic and extrinsic factors. Therefore, a newly formulated technology should be introduced into the treatment process to substantiate efficacy and efficiency. Nanotechnology-based wound care materials are getting awesome responses from medical research fraternities owing to their unique physic-chemical properties and pose precise targeting of wound infection at various stages in the healing process. Among the nanomaterials, Graphene Oxide (GO) carbon allotrope is intensively used in various wound healing applications. These oxide nanomaterials are biocompatible, biodegradable, easily functionalized with drugs, have surface modification and charge, and are rapidly internalized in the cell membrane. These qualitative properties merit the use of GO in treating chronic and non-chronic wounds. Therefore, the present review emphasizes the role of Graphene oxide in the wound healing process and explains its molecular dynamics in the healing process.