Fatty acid binding protein 7 mediates linoleic acid-induced cell death in triple negative breast cancer cells by modulating 13-HODE

• Main Authors: Kwong, Soke Chee, Abd Jamil, Amira Hajirah, Rhodes, Anthony, Taib, Nur Aishah, Chung, Ivy
• Format: Article
• Published: Elsevier 2020
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/36221/; https://www.scopus.com/record/display.uri?eid=2-s2.0-85091080603&origin=resultslist&sort=plf-f&src=s&sid=d5c0fe81c8d4c799ccb17c3d64c91be5&sot=b&sdt=b&s=TITLE-ABS-KEY%28Fatty+acid+binding+protein+7+mediates+linoleic+acid-induced+cell+death+in+triple+negative+breast+cancer+cells+by+modulating+13-HODE%29&sl=146&sessionSearchId=d5c0fe81c8d4c799ccb17c3d64c91be5

Different fatty acids have distinct effects on the survival of breast cancer cells, which could be mediated by fatty acid binding proteins (FABPs), a family of lipid chaperones. Due to the diverse structures of the members of FABP family, each FABP demonstrates distinct binding affinities to differe...