Association of pre-diagnostic antibody responses to escherichia coli and bacteroides fragilis toxin proteins with colorectal cancer in a European cohort

• Main Authors: Butt, Julia, Jenab, Mazda, Werner, Jill, Fedirko, Veronika, Weiderpass, Elisabete, Dahm, Christina C., Tjonneland, Anne, Olsen, Anja, Boutron-Ruault, Marie-Christine, Rothwell, Joseph A., Severi, Gianluca, Kaaks, Rudolf, Turzanski-Fortner, Renee, Aleksandrova, Krasimira, Schulze, Matthias, Palli, Domenico, Pala, Valeria, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, Bueno-de-Mesquita, Bas, Van Gils, Carla H., Gram, Inger Torhild, Lukic, Marko, Sala, Nuria, Sanchez Perez, Maria Jose, Ardanaz, Eva, Chirlaque, Maria-Dolores, Palmquist, Richard, Lowenmark, Thyra, Travis, Ruth C., Heath, Alicia, Cross, Amanda J., Freisling, Heinz, Zouiouich, Semi, Aglago, Elom, Waterboer, Tim, Hughes, David J.
• Format: Article
• Published: Taylor & Francis 2021
• Subjects: R Medicine; RC Internal medicine; RC0254 Neoplasms. Tumors. Oncology (including Cancer); RD Surgery
• Online Access: http://eprints.um.edu.my/34687/

Experimental evidence has implicated genotoxic Escherichia coli (E. coli) and enterotoxigenic Bacteroides fragilis (ETBF) in the development of colorectal cancer (CRC). However, evidence from epidemiological studies is sparse. We therefore assessed the association of serological markers of E. coli a...