Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes

• Main Authors: Vuong, Nguyen Lam, Lam, Phung Khanh, Ming, Damien Keng Yen, Duyen, Huynh Thi Le, Nguyen, Nguyet Minh, Tam, Dong Thi Hoai, Hue, Kien Duong Thi, Chau, Nguyen V. V., Chanpheaktra, Ngoun, Lum, Lucy Chai See, Pleites, Ernesto, Simmons, Cameron P., Rosenberger, Kerstin D., Jaenisch, Thomas, Bell, David, Acestor, Nathalie, Halleux, Christine, Olliaro, Piero L., Wills, Bridget A., Geskus, Ronald B., Yacoub, Sophie
• Format: Article
• Published: eLife Sciences Publications 2021
• Subjects: R Medicine; RA Public aspects of medicine
• Online Access: http://eprints.um.edu.my/34643/

Background: Early identification of severe dengue patients is important regarding patient management and resource allocation. We investigated the association of 10 biomarkers (VCAM-1, SDC-1, Ang-2, IL-8, IP-10, IL-1RA, sCD163, sTREM-1, ferritin, CRP) with the development of severe/ moderate dengue (...