Association study of MCCC1/LAMP3 and DGKQ variants with Parkinson's disease in patients of Malay ancestry

• Main Authors: Lim, Jia Lun, Ng, Ebonne Yulin, Lim, Shen-Yang, Tan, Ai Huey, Abdul-Aziz, Zariah, Ibrahim, Khairul Azmi, Gopalai, Aroma Agape, Tay, Yi Wen, Vijayanathan, Yuganthini, Toh, Tzi Shin, Lim, Soo Kun, Bee, Ping-Chong, Puvanarajah, Santhi Datuk, Viswanathan, Shanthi, Looi, Irene, Lim, Thien Thien, Eow, Gaik Bee, Cheah, Wee Kooi, Tan, Eng-King, Ahmad-Annuar, Azlina
• Format: Article
• Published: Springer-Verlag Italia Srl 2021
• Subjects: R Medicine; RC Internal medicine
• Online Access: http://eprints.um.edu.my/34634/

Background Genome-wide association studies (GWAS) have shown that variants in the 3-methylcrotonyl-CoA carboxylase (MCCC1)/lysosome-associated membrane protein 3 (LAMP3) loci (rs10513789, rs12637471, rs12493050) reduce the risk of Parkinson's disease (PD) in Caucasians, Chinese and Ashkenazi-Je...