A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease

• Main Authors: Zain, S.M., Mohamed, R., Mahadeva, S., Cheah, P.L., Rampal, S., Basu, R.C., Mohamed, Z.
• Format: Article
• Language: English
• Published: 2012
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/3462/1/24.pdf; http://eprints.um.edu.my/3462/; http://www.ncbi.nlm.nih.gov/pubmed/22258181

The adiponutrin (PNPLA3) rs738409 polymorphism has been found to be associated with susceptibility to non-alcoholic fatty liver disease (NAFLD) in various cohorts. We further investigated the association of this polymorphism with non-alcoholic steatohepatitis (NASH) severity and with histological fe...