Construction of a microRNA-mRNA regulatory network in de novo cytogenetically normal acute myeloid leukemia patients

• Main Authors: Esa, Ezalia, Hashim, Ariwibawa Kasmani, Mohamed, Elsa Haniffah Mejia, Zakaria, Zubaidah, Abu Hassan, Alifah Nadia, Yusoff, Yuslina Mat, Kamaluddin, Nor Rizan, Rahman, Ahmad Zuhairi Abdul, Chang, Kian-Meng, Mohamed, Rashidah, Subbiah, Indhira, Jamian, Ehram, Ho, Caroline Siew-Ling, Lim, Soo-Min, Lau, Peng-Choon, Pung, Yuh-Fen, Zain, Shamsul Mohd
• Format: Article
• Published: Mary Ann Liebert, Inc 2021
• Subjects: R Medicine; R Medicine (General)
• Online Access: http://eprints.um.edu.my/34598/

Background: The association between dysregulated microRNAs (miRNAs) and acute myeloid leukemia (AML) is well known. However, our understanding of the regulatory role of miRNAs in the cytogenetically normal AML (CN-AML) subtype pathway is still poor. The current study integrated miRNA and mRNA profil...