Forrestiacids A and B, pentaterpene inhibitors of ACL and lipogenesis: Extending the limits of computational NMR methods in the structure assignment of complex natural products

• Main Authors: Xiong, Juan, Zhou, Peng-Jun, Jiang, Hao-Wen, Huang, Ting, He, Yu-Hang, Zhao, Ze-Yu, Zang, Yi, Choo, Yeun-Mun, Wang, Xiaojuan, Chittiboyina, Amar G., Pandey, Pankaj, Hamann, Mark T., Li, Jia, Hu, Jin-Feng
• Format: Article
• Published: Wiley 2021
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/34581/

Forrestiacids A (1) and B (2) are a novel class of 4+2] type pentaterpenoids derived from a rearranged lanostane moiety (dienophile) and an abietane unit (diene). These unprecedented molecules were isolated using guidance by molecular ion networking (MoIN) from Pseudotsuga forrestii, an endangered m...