Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population
Addressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men. Method This was a cross-sectional study that recruited 503 healthy males from 3 c...
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my.um.eprints.345292022-09-15T02:31:07Z http://eprints.um.edu.my/34529/ Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population Khoo, Su Pei Shafii, Mohd Khairul Anwar Bhoo-Pathy, Nirmala Yap, Siew Hwei Subramaniam, Shridevi Nasir, Nazrila Hairizan Lin, Zhang Belinson, Jerome Goh, Pik Pin Qu, Xinfeng Gravitt, Patti Woo, Yin Ling R Medicine RA Public aspects of medicine RA0421 Public health. Hygiene. Preventive Medicine RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) Addressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men. Method This was a cross-sectional study that recruited 503 healthy males from 3 community-based clinics in Selangor, Malaysia. Genital and anal samples were collected from each participant for 14 high risk and 2 low risk HPV DNA detection and genotyping. All participants responded to a set of detailed sociodemographic and sexual behaviour questionnaire. Results The median age at enrolment was 40 years old (IQR: 31-50). The anogenital HPV6/11 prevalence was 3.2% whereas high risk HPV prevalence was 27.1%. The genital HPV prevalence for HPV6/11 was 2.9% while high risk HPV was 18.8%. HPV6/11 prevalence in the anal canal was 1.6% and high risk HPV was 12.7%. HPV 18 was the most prevalent genotype detected in the anogenital area. There was a significant independent association between genital and anal HPV infections. Conclusion Anogenital HPV infection is common among Malaysian men. These findings emphasize the ubiquity of HPV infection and thus the value of population-wide access to HPV prevention. Public Library of Science 2021-01-20 Article PeerReviewed Khoo, Su Pei and Shafii, Mohd Khairul Anwar and Bhoo-Pathy, Nirmala and Yap, Siew Hwei and Subramaniam, Shridevi and Nasir, Nazrila Hairizan and Lin, Zhang and Belinson, Jerome and Goh, Pik Pin and Qu, Xinfeng and Gravitt, Patti and Woo, Yin Ling (2021) Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population. PLoS ONE, 16 (1). ISSN 1932-6203, DOI https://doi.org/10.1371/journal.pone.0245731 <https://doi.org/10.1371/journal.pone.0245731>. 10.1371/journal.pone.0245731 |
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R Medicine RA Public aspects of medicine RA0421 Public health. Hygiene. Preventive Medicine RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
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R Medicine RA Public aspects of medicine RA0421 Public health. Hygiene. Preventive Medicine RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) Khoo, Su Pei Shafii, Mohd Khairul Anwar Bhoo-Pathy, Nirmala Yap, Siew Hwei Subramaniam, Shridevi Nasir, Nazrila Hairizan Lin, Zhang Belinson, Jerome Goh, Pik Pin Qu, Xinfeng Gravitt, Patti Woo, Yin Ling Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
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Addressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men. Method This was a cross-sectional study that recruited 503 healthy males from 3 community-based clinics in Selangor, Malaysia. Genital and anal samples were collected from each participant for 14 high risk and 2 low risk HPV DNA detection and genotyping. All participants responded to a set of detailed sociodemographic and sexual behaviour questionnaire. Results The median age at enrolment was 40 years old (IQR: 31-50). The anogenital HPV6/11 prevalence was 3.2% whereas high risk HPV prevalence was 27.1%. The genital HPV prevalence for HPV6/11 was 2.9% while high risk HPV was 18.8%. HPV6/11 prevalence in the anal canal was 1.6% and high risk HPV was 12.7%. HPV 18 was the most prevalent genotype detected in the anogenital area. There was a significant independent association between genital and anal HPV infections. Conclusion Anogenital HPV infection is common among Malaysian men. These findings emphasize the ubiquity of HPV infection and thus the value of population-wide access to HPV prevention. |
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Article |
author |
Khoo, Su Pei Shafii, Mohd Khairul Anwar Bhoo-Pathy, Nirmala Yap, Siew Hwei Subramaniam, Shridevi Nasir, Nazrila Hairizan Lin, Zhang Belinson, Jerome Goh, Pik Pin Qu, Xinfeng Gravitt, Patti Woo, Yin Ling |
author_facet |
Khoo, Su Pei Shafii, Mohd Khairul Anwar Bhoo-Pathy, Nirmala Yap, Siew Hwei Subramaniam, Shridevi Nasir, Nazrila Hairizan Lin, Zhang Belinson, Jerome Goh, Pik Pin Qu, Xinfeng Gravitt, Patti Woo, Yin Ling |
author_sort |
Khoo, Su Pei |
title |
Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
title_short |
Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
title_full |
Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
title_fullStr |
Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
title_full_unstemmed |
Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population |
title_sort |
prevalence and sociodemographic correlates of anogenital human papillomavirus (hpv) carriage in a cross-sectional, multi-ethnic, community-based asian male population |
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Public Library of Science |
publishDate |
2021 |
url |
http://eprints.um.edu.my/34529/ |
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1744649184889274368 |
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13.19449 |