Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity

• Main Authors: Ilyas, Shazia, Tabasum, Raheela, Iftikhar, Ali, Nazir, Mamoona, Hussain, Amina, Hussain, Aroosha, Ali, Muhammad Sajjad, Saleem, Farooq, Saleem, Uzma, Froeyen, Matheus, Abdullah, Iskandar, Mirza, Muhammad Usman, Ahmad, Sarfraz
• Format: Article
• Published: Nature Research 2021
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/34520/

Ifosfamide is a widely used chemotherapeutic agent having broad-spectrum efficacy against several tumors. However, nephro, hepato, neuro cardio, and hematological toxicities associated with ifosfamide render its use limited. These side effects could range from organ failure to life-threatening situa...