Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis

Background Trauma mortality in low- and middle-income countries (LMICs) remains high compared to high-income countries. Quality improvement processes, interventions, and structure are essential in the effort to decrease trauma mortality. Methods A systematic review and meta-analysis of interventiona...

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Main Authors: Jin, James, Akau'ola, Salesi', Yip, Cheng-Har, Nthumba, Peter, Ameh, Emmanuel A., de Jonge, Stijn, Mehes, Mira, Waiqanabete, Iferemi, Henry, Jaymie, Hill, Andrew
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Published: Springer Verlag (Germany) 2021
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Online Access:http://eprints.um.edu.my/34356/
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spelling my.um.eprints.343562022-06-09T06:36:14Z http://eprints.um.edu.my/34356/ Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis Jin, James Akau'ola, Salesi' Yip, Cheng-Har Nthumba, Peter Ameh, Emmanuel A. de Jonge, Stijn Mehes, Mira Waiqanabete, Iferemi Henry, Jaymie Hill, Andrew RD Surgery Background Trauma mortality in low- and middle-income countries (LMICs) remains high compared to high-income countries. Quality improvement processes, interventions, and structure are essential in the effort to decrease trauma mortality. Methods A systematic review and meta-analysis of interventional studies assessing quality improvement processes, interventions, and structure in developing country trauma systems was conducted from November 1989 to August 2020 according to the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were included if they were conducted in an LMIC population according to World Bank Income Classification, occurred in a trauma setting, and measured the effect of implementation and its impact. The primary outcome was trauma mortality. Results Of 37,575 search results, 30 studies were included from 15 LMICs covering five WHO regions in a qualitative synthesis. Twenty-seven articles were included in a meta-analysis. Implementing a pre-hospital trauma system reduced overall trauma mortality by 45% (risk ratio (RR) 0.55, 95% CI 0.4 to 0.75). Training first responders resulted in an overall decrease in mortality (RR 0.47, 95% CI 0.28 to 0.78). In-hospital trauma training with certified courses resulted in a reduction of mortality (RR 0.71, 95% CI 0.62 to 0.78). Trauma audits and trauma protocols resulted in varying improvements in trauma mortality. Conclusion There is evidence that quality improvement processes, interventions, and structure can improve mortality in the trauma systems in LMICs. Springer Verlag (Germany) 2021-07 Article PeerReviewed Jin, James and Akau'ola, Salesi' and Yip, Cheng-Har and Nthumba, Peter and Ameh, Emmanuel A. and de Jonge, Stijn and Mehes, Mira and Waiqanabete, Iferemi and Henry, Jaymie and Hill, Andrew (2021) Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis. World Journal of Surgery, 45 (7). pp. 1982-1998. ISSN 0364-2313, DOI https://doi.org/10.1007/s00268-021-06065-9 <https://doi.org/10.1007/s00268-021-06065-9>. 10.1007/s00268-021-06065-9
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic RD Surgery
spellingShingle RD Surgery
Jin, James
Akau'ola, Salesi'
Yip, Cheng-Har
Nthumba, Peter
Ameh, Emmanuel A.
de Jonge, Stijn
Mehes, Mira
Waiqanabete, Iferemi
Henry, Jaymie
Hill, Andrew
Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
description Background Trauma mortality in low- and middle-income countries (LMICs) remains high compared to high-income countries. Quality improvement processes, interventions, and structure are essential in the effort to decrease trauma mortality. Methods A systematic review and meta-analysis of interventional studies assessing quality improvement processes, interventions, and structure in developing country trauma systems was conducted from November 1989 to August 2020 according to the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were included if they were conducted in an LMIC population according to World Bank Income Classification, occurred in a trauma setting, and measured the effect of implementation and its impact. The primary outcome was trauma mortality. Results Of 37,575 search results, 30 studies were included from 15 LMICs covering five WHO regions in a qualitative synthesis. Twenty-seven articles were included in a meta-analysis. Implementing a pre-hospital trauma system reduced overall trauma mortality by 45% (risk ratio (RR) 0.55, 95% CI 0.4 to 0.75). Training first responders resulted in an overall decrease in mortality (RR 0.47, 95% CI 0.28 to 0.78). In-hospital trauma training with certified courses resulted in a reduction of mortality (RR 0.71, 95% CI 0.62 to 0.78). Trauma audits and trauma protocols resulted in varying improvements in trauma mortality. Conclusion There is evidence that quality improvement processes, interventions, and structure can improve mortality in the trauma systems in LMICs.
format Article
author Jin, James
Akau'ola, Salesi'
Yip, Cheng-Har
Nthumba, Peter
Ameh, Emmanuel A.
de Jonge, Stijn
Mehes, Mira
Waiqanabete, Iferemi
Henry, Jaymie
Hill, Andrew
author_facet Jin, James
Akau'ola, Salesi'
Yip, Cheng-Har
Nthumba, Peter
Ameh, Emmanuel A.
de Jonge, Stijn
Mehes, Mira
Waiqanabete, Iferemi
Henry, Jaymie
Hill, Andrew
author_sort Jin, James
title Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
title_short Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
title_full Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
title_fullStr Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
title_full_unstemmed Effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: A systematic review and meta-analysis
title_sort effectiveness of quality improvement processes, interventions, and structure in trauma systems in low- and middle-income countries: a systematic review and meta-analysis
publisher Springer Verlag (Germany)
publishDate 2021
url http://eprints.um.edu.my/34356/
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score 13.211869