In silico studies of fisetin and silymarin as novel chikungunya virus nonstructural proteins inhibitors

• Main Authors: Lani, Rafidah, Agharbaoui, Fatima Ezzahra, Hassandarvish, Pouya, Teoh, Boon Teong, Sam, Sing Sin, Zandi, Keivan, Rahman, Noorsaadah Abd, AbuBakar, Sazaly
• Format: Article
• Published: Future Medicine Ltd 2021
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/34041/

Aim: Chikungunya virus (CHIKV) infection is often characterized by fever, rash and arthralgia. Until now, there is no vaccine or antiviral drug available for this disease. Two flavonoid compounds, silymarin and fisetin, were reported to be able to inhibit CHIKV replication. Materials & methods:...